CANDIDA SPECIES IN THE GENITAL TRACT OF WOMEN ATTENDING A UNIVERSITY HOSPITAL FOR GYNECOLOGICAL INTERVENTIONS

Autores

  • Thais Chimati Felix Programa de Pós-graduação em Ciências da Saúde Faculdade de Medicina Universidade Federal de Uberlândia
  • Ralciane de Paula Menezes Curso Técnico em Análises Clínicas Escola Técnica de Saúde Universidade Federal de Uberlândia
  • Marilia Cristina Berardi Programa de Pós-graduação em Ciências da Saúde Faculdade de Medicina Universidade Federal de Uberlândia
  • Denise Von Dolinger de Brito Röder Instituto de Ciências Biomédicas Universidade Federal de Uberlândia
  • Reginaldo dos Santos Pedroso Curso Técnico em Análises Clínicas Escola Técnica de Saúde Universidade Federal de Uberlândia http://orcid.org/0000-0003-3010-5754

DOI:

https://doi.org/10.17267/2317-3386bjmhh.v5i1.1254

Palavras-chave:

candidiasis, Women's health, Signs and symptoms

Resumo

Introduction: Vulvovaginal candidiasis occurs in about 75% of all women during reproductive age, and around half of those will have at least one recurrent episode. Objectives: To evaluate the occurrence of Candida species in the genital tract of women attending a clinic of Gynecology and Obstetrics at the University Hospital for gynecological interventions, related to signs and symptoms of infection and also to evaluate the susceptibility to antifungal agents of the Candida isolates. Methods and materials: Samples of vaginal secretions were taken of 128 women during gynecological and colposcopic examination, through sterile swab, to carry out culture for fungi. Susceptibility tests were performed for fluconazole, itraconazole, voriconazole, nystatin and amphotericin B. Results: Twenty (15.6%) patients had positive culture for yeasts identified as: C. albicans (57.1%), C. glabrata (19%), C. parapsilosis complex (4.8%), C. lipolytica (4.8%), Trichosporon sp (9.5%), and Rhodotorula sp (4.8%). Ninety women (70.3%) reported no symptoms and 38 (29.6%) were symptomatic. The most frequent complaints were: discharge, vulval itching, and dyspareunia. All isolates were susceptible to the antifungal agents tested, except for some isolates of C. parapsilosis complex, which showed in vitro resistance to itraconazole. Conclusions: Although Candida species were isolated in only some of the women, C. albicans was the most common species. The more frequent complaints were discharge and vulvar itching. Most of the isolates were susceptible to the antifungals tested.

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2017-03-27

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