Development of a low-cost device for photobiomodulation using 3D printing

Authors

DOI:

https://doi.org/10.17267/2965-3738bis.2024.e5306

Keywords:

Phototherapy, Diffusion of Innovation, Physical Therapy Modalities

Abstract

INTRODUCTION: Photobiomodulation therapy (PBM) is a non-pharmacological and non-invasive therapeutic strategy that has shown promising results in several health conditions. Despite important advances in knowledge of its modulatory effects at the molecular, cellular, and tissue levels, the cost of PBM equipment still greatly limits its use in the clinical setting, especially in developing countries. In this context, the use of new technologies such as 3D printing has presented several possibilities for application in the health area. OBJECTIVES: To develop a 3D printing PBM device and test its technical and operational viability. METHODS AND MATERIALS: Development of Health Technology on a Photobiomodulation Device with 3D Printing Tests of the safety, emission, and support of the light beams were carried out. RESULTS: The PBM device demonstrated operational safety and good quality in the maintenance of light beams. CONCLUSION: A three-dimensional (3D) printed LED PBM device is technically, operationally, and financially viable. However, more experimental tests and clinical validation are required before this prototype can be used in human health applications.

Author Biographies

  • Renato Dias dos Santos, Universidade Federal do Delta do Parnaíba (Parnaíba). Piauí, Brazil.

     

     

     

  • Wilson Rosas de Vasconcelos Neto, Instituto Federal do Piauí (Parnaíba). Piauí, Brazil.

     

     

     

  • Vinicius Saura Cardoso, Universidade Federal do Delta do Parnaíba (Parnaíba). Piauí, Brazil.

     

     

  • Raquel Sales Rocha Jacob, Universidade Federal do Delta do Parnaíba (Parnaíba). Piauí, Brazil.

     

     

  • Lana Paula Cardoso Moreira, Universidade Federal do Delta do Parnaíba (Parnaíba). Piauí, Brazil.

     

     

  • Fuad Hazime, Universidade Federal do Delta do Parnaíba (Parnaíba). Piauí, Brazil.

     

     

     

References

(1) Clijsen R, Brunner A, Barbero M, Clarys P, Taeymans J. Effects of low-level laser therapy on pain in patients with musculoskeletal disorders: a systematic review and meta-analysis. Eur J Phys Rehabil Med. 2017;53(4):603-10. http://dx.doi.org/10.23736/S1973-9087.17.04432-X

(2) Darwin E, Heyes A, Hirt PA, Wikramanayake TC, Jimenez JJ. Low-level laser therapy for the treatment of androgenic alopecia: a review. Lasers Med Sci. 2018;33(2):425-34. http://dx.doi.org/10.1007/s10103-017-2385-5

(3) Li S, Wang C, Wang B, Liu L, Tang L, Liu D, et al. Efficacy of low-level light therapy for treatment of diabetic foot ulcer: A systematic review and meta-analysis of randomized controlled trials. Diabetes Res Clin Pract. 2018;143:215-24. http://dx.doi.org/10.1016/j.diabres.2018.07.014

(4) Yeh S-W, Hong C-H, Shih M-C, Tam K-W, Huang Y-H, Kuan Y-C. Low-Level Laser Therapy for Fibromyalgia: A Systematic Review and Meta-Analysis. Pain Physician. 2019;22(3):241-54. Cited: PMID: 31151332.

(5) Jana Neto FC, Martimbianco ALC, Andrade RP, Bussadori SK, Mesquita-Ferrari RA, Fernandes KPS. Effects of photobiomodulation in the treatment of fractures: a systematic review and meta-analysis of randomized clinical trials. Lasers Med Sci. 2020;35(3):513-22. http://dx.doi.org/10.1007/s10103-019-02779-4

(6) Gao Y, An R, Huang X, Liu W, Yang C, Wan Q. Effectiveness of photobiomodulation for people with age-related cognitive impairment: a systematic review and meta-analysis. Lasers Med Sci. 2023;38(1):237. http://dx.doi.org/10.1007/s10103-023-03899-8

(7) Costa MS, Brito TV, Oliveira SB, Brauna IS, Mazulo Neto JCR, Teles RHG, et al. Photobiomodulation exerts anti-inflammatory effects on the vascular and cellular phases of experimental inflammatory models. Lasers Med Sci. 2022;37(1):563-71. http://dx.doi.org/10.1007/s10103-021-03298-x

(8) Zein R, Selting W, Hamblin MR. Review of light parameters and photobiomodulation efficacy: dive into complexity. J Biomed Opt. 2018;23(12):120901. http://dx.doi.org/10.1117/1.JBO.23.12.120901

(9) Toma RL, Oliveira MX, Renno ACM, Laakso E-L. Photobiomodulation (PBM) therapy at 904 nm mitigates effects of exercise-induced skeletal muscle fatigue in young women. Lasers Med Sci. 2018;33(6):1197-205. http://dx.doi.org/10.1007/s10103-018-2454-4

(10) Langella LG, Casalechi HL, Tomazoni SS, Johnson DS, Albertini R, Pallotta RC, et al. Photobiomodulation therapy (PBMT) on acute pain and inflammation in patients who underwent total hip arthroplasty-a randomized, triple-blind, placebo-controlled clinical trial. Lasers Med Sci. 2018;33(9):1933-40. http://dx.doi.org/10.1007/s10103-018-2558-x

(11) Santos JAF, Campelo MBD, Oliveira RA, Nicolau RA, Rezende VEA, Arisawa EAL. Effects of Low-Power Light Therapy on the Tissue Repair Process of Chronic Wounds in Diabetic Feet. Photomed Laser Surg. 2018;36(6):298-304. http://dx.doi.org/10.1089/pho.2018.4455

(12) Vitoriano NAM, Mont’Alverne DGB, Martins MIS, Silva PS, Martins CA, Teixeira HD, et al. Comparative study on laser and LED influence on tissue repair and improvement of neuropathic symptoms during the treatment of diabetic ulcers. Lasers Med Sci. 2019;34(7):1365-71. http://dx.doi.org/10.1007/s10103-019-02724-5

(13) Poorpezeshk N, Ghoreishi SK, Bayat M, Pouriran R, Yavari M. Early Low-Level Laser Therapy Improves the Passive Range of Motion and Decreases Pain in Patients with Flexor Tendon Injury. Photomed Laser Surg. 2018;36(10):530-5. http://dx.doi.org/10.1089/pho.2018.4458

(14) Chung H, Dai T, Sharma SK, Huang Y-Y, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012;40(2):516-33. http://dx.doi.org/10.1007/s10439-011-0454-7

(15) Souza CG, Borges DT, Macedo LB, Brasileiro JS. Low-level laser therapy reduces the fatigue index in the ankle plantar flexors of healthy subjects. Lasers Med Sci. 2016;31(9):1949-55. http://dx.doi.org/10.1007/s10103-016-2074-9

(16) Hemmings TJ, Kendall KL, Dobson JL. Identifying Dosage Effect of Light-Emitting Diode Therapy on Muscular Fatigue in Quadriceps. J Strength Cond Res. 2017;31(2):395-402. http://dx.doi.org/10.1519/JSC.0000000000001523

(17) Lanferdini FJ, Krüger RL, Baroni BM, Lazzari C, Figueiredo P, Reischak-Oliveira A, et al. Low-level laser therapy improves the VO2 kinetics in competitive cyclists. Lasers Med Sci. 2018;33(3):453-60. http://dx.doi.org/10.1007/s10103-017-2347-y

(18) Fisher SR, Rigby JH, Mettler JA, McCurdy KW. The Effectiveness of Photobiomodulation Therapy Versus Cryotherapy for Skeletal Muscle Recovery: A Critically Appraised Topic. J Sport Rehabil. 2019;28(5):526-31. http://dx.doi.org/10.1123/jsr.2017-0359

(19) Ferraresi C, Huang Y-Y, Hamblin MR. Photobiomodulation in human muscle tissue: an advantage in sports performance?. J Biophotonics. 2016;9(11-12):1273-99. http://dx.doi.org/10.1002/jbio.201600176

(20) Javaid M, Haleem A, Singh RP, Suman R. 3D printing applications for healthcare research and development. Glob Health J. 2022;6(4):217-26. http://dx.doi.org/10.1016/j.glohj.2022.11.001

(21) Mamo HB, Adamiak M, Kunwar A. 3D printed biomedical devices and their applications: A review on state-of-the-art technologies, existing challenges, and future perspectives. J Mech Behav Biomed Mater. 2023;143:105930. http://dx.doi.org/10.1016/j.jmbbm.2023.105930

(22) Arduino. Homepage [Internet]. [s.d.]. Available from: https://www.arduino.cc/

(23) Evans SR. Fundamentals of clinical trial design. J Exp Stroke Transl Med. 2010;3(1):19-27. Cited: PMID: 21533012.

(24) Cruz AR, Minicucci EM, Betini M, Almeida-Lopes L, Tieghi Neto V, Cataneo AJM. Efficacy of photobiomodulation in the treatment of oral mucositis in patients undergoing antineoplastic therapy: systematic review and meta-analysis. Support Care Cancer. 2023;31(12):645. http://dx.doi.org/10.1007/s00520-023-08105-7

(25) Ngoc LTN, Moon J-Y, Lee Y-C. Utilization of light-emitting diodes for skin therapy: Systematic review and meta-analysis. Photodermatol Photoimmunol Photomed. 2023;39(4):303-17. http://dx.doi.org/10.1111/phpp.12841

(26) Martin PI, Chao L, Krengel MH, Ho MD, Yee M, Lew R, et al. Transcranial Photobiomodulation to Improve Cognition in Gulf War Illness. Front Neurol. 2020;11:574386. http://dx.doi.org/10.3389/fneur.2020.574386

(27) Vanin AA, Verhagen E, Barboza SD, Costa LOP, Leal-Junior ECP. Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis. Lasers Med Sci. 2018;33(1):181-214. http://dx.doi.org/10.1007/s10103-017-2368-6

Downloads

Published

03/19/2024

Issue

Vol. 3 (2024)

Section

Technology and methodological perspectives

License

Copyright (c) 2024 Renato Dias dos Santos, Wilson Rosas de Vasconcelos Neto, Vinicius Saura Cardoso, Raquel Sales Rocha Jacob, Lana Paula Cardoso Moreira, Fuad Hazime

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License

How to Cite

1.
dos Santos RD, Neto WR de V, Cardoso VS, Jacob RSR, Moreira LPC, Hazime F. Development of a low-cost device for photobiomodulation using 3D printing. Brain Imaging and Stimul. [Internet]. 2024 Mar. 19 [cited 2024 Dec. 21];3:e5306. Available from: https://journals.bahiana.edu.br/index.php/brain/article/view/5306

Most read articles by the same author(s)

1 2 3 > >>