Effects of carboxiterapia on health wound healing

Abstract

INTRODUCTION: New therapies for difficult-to-heal injuries have become necessary and are being researched. In this context, carboxytherapy has been highlighted by its effects on tissue microcirculation. OBJECTIVE: evaluate the effects of carboxytherapy, infusion in the subcutaneous tissue of medicinal CO2, in the healing of skin lesions in Wistars rats. MATERIALS AND METHODS: This is an experimental and quantitative study, with a sample of 10 animals divided into a control group and a carboxytherapy group. All the animals suffered a metallic punch injury of 5mm diameter in the dorsal region and the group with therapy, treated for 10 consecutive days. The region was photographed at various times of the research and then the images were analyzed by ImageJ software. RESULTS: In the descriptive analysis of the data, the CG presented a progressive reduction of the area of 0.205 ± 0.025 to 0.155 ± 0.017 on the 3rd day, 0.109 ± 0.034 on the 7th day and 0.028 ± 0.092 after the 10th day, GCa presented an area increase of 0.198 ± 0.040 for 0.207 ± 0.035 on the 3rd day, with reduction to 0.109 ± 0.012 on the 7th day and 0.044 ± 0.030 after 10 days, demonstrating to be less efficient in the healing of cutaneous wounds than the absence of treatment. CONCLUSION: Carboxitherapy did not show significant results to accelerate the healing process of cutaneous lesions in the acute phase, suggesting this period as not ideal for its use.